Compare prices, print coupons and get savings tips for deferoxamine generic desferal and other iron overload drugs at cvs, walgreens, and other pharmacies. Eligibility is often based on income, insurance or medicare status, and other factors. What are some things i need to know or do while i take deferoxamine. Mucormycosis during deferoxamine therapy is a siderophore. Deferoxamine binds to iron and removes it from the blood stream. It works by helping the kidneys and gallbladder get rid of the extra iron. Medications listed here may also be marketed under different names in different countries. The drug should ordinarily not be given to such patients unless significant iron mobilization e. Nonus country and region specific information is not available on this page. India torrent pharma, the flagship company of the torrent group, is one of the leading pharma companies in india.
Inquire about dmf, cgmp, price, availability, samples, sourcing, purity and more. The drug should be completely dissolved before the solution is withdrawn. Deferoxamine mesylate for injection, usp reconstituted with sterile water for injection is for singledose only. Find patient medical information for deferoxamine injection on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Note that not all products are shipped by our contracted canadian pharmacy. The following program is offered by the manufacturer of this drug.
Deferoxamine may also be used for purposes not listed in this medication guide. Deferoxamine side effects, dosage, interactions drugs. Deferoxamine is a member of the antidotes drug class and is commonly used for iron poisoning acute and iron poisoning chronic. Deferoxamine mesylate for injection reconstituted with sterile water for. Webmd provides common contraindications for deferoxamine injection. At torrent, we strongly believe in providing quality medicines at affordable price to the patients. Deferoxamine chelates iron from intralysosomal ferritin and siderin forming ferrioxamine, a watersoluble chelate excreted by the kidneys and in the feces via the bile. This agent does not readily bind iron from transferrin, hemoglobin, myoglobin or cytochrome. Food and drug administration 10903 new hampshire avenue silver spring, md 20993 1888infofda 18884636332 contact fda. Conceived as a small generic company in the early 70s by late shri u n mehta, torrent pharma blazed a new trail in the indian pharmaceuticals industry by successfully implementing the concept of niche marketing. Deferoxamine injection is used to remove excess iron from the body in anemia or thalassemia patients who have many blood transfusions. Look up information on diseases, tests, and procedures.
For general medical information or questions about a specific medical condition or product, please consult your healthcare provider. Theoretically, 100 parts by weight of deferoxamine mesylate is capable of binding approximately 8. Deferoxamine dfoa, sold under the brand name desferal, is a medication that binds iron and aluminium. Torrent recalls more than 1m bottles of tainted blood pressure drugs. Learn about drug imprint, side effects, uses treating, dosage, interaction, overdose, and warnings.
Deferoxamine binds to iron and removes it from the bloodstream. Torrent pharmaceuticals limited manufactures, markets andor distributes more than 43 drugs in the united states. A year after torrent pharmaceuticals first began recalling tainted losartan products manufactured at its indrad plant, the fda paid a visit. The drug will be reconstituted for injection, by dissolving in 20 ml of sterile water. High dose deferoxamine in intracerebral hemorrhage full. In this quest, primarily, we have inclined ourselves towards safeguarding both the qualitative and quantitative aspects with the help of our robust manufacturing technologies and manufacturing facilities. It is also used with other medicines to treat acute iron poisoning, especially in small children. It is specifically used in iron overdose, hemochromatosis either due to multiple blood transfusions or an underlying genetic condition, and aluminium toxicity in people on dialysis.
Desferal is supplied as vials containing 500 mg and 2 g of deferoxamine mesylate usp in sterile, lyophilized form. Desferal deferoxamine dosing, indications, interactions. Deferoxamine is used to treat iron overload caused by blood transfusions in adults and children at least 3 years old. Conceived as a small generic company in the early 70s by late shri u n mehta, torrent pharma blazed a new trail in the indian pharmaceuticals industry by. Deferoxamine drug information indications, dosage, side. Deferoxamine is used to treat acute immediate iron overdose. Deferoxamine mesylate api manufacturers suppliers drug.
Deferoxamine is not indicated for the treatment of primary hemochromatosis treatment of. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment andor medical condition advice. Consumer information about the medication deferoxamine injection desferal, includes side effects, drug interactions, recommended dosages, and storage information. It is used by injection into a muscle, vein, or under the skin.
This medication is not recommended for use in children less than 3 years old see also precautions section. As such, this web site can not guarantee the reliability, accuracy, and or medical efficacy of the information provided. The combination of iron and deferoxamine is then removed from the body by the kidneys. It found a plant that often routinely reported products. You must check to make sure that it is safe for you to take deferoxamine with all of your drugs and health problems. Desferal deferoxamine mesylate injection, powder, lyophilized, for solution if this spl contains inactivated ndcs listed by the fda initiated compliance action, they will. Listing a study does not mean it has been evaluated by the u. Torrent pharmaceuticals limited is expanding its voluntary recall from 2 lots of losartan potassium tablets usp to a total of 10 lots, to the.
Deferoxamine will not be covered for use in the diagnosis or treatment of aluminum toxicity in patients with ckd undergoing maintenance dialysis as these are unlabeled uses. Deferoxamine mesylate usp is not indicated for the treatment of primary hemochromatosis, since phlebotomy is the method of choice for removing excess iron in this disorder. Pfizer has deferoxamine on shortage due to manufacturing delays. Dailymed deferoxamine deferoxamine mesylate injection. Torrent pharmaceuticals limited expands voluntary nationwide. The nlm drug information portal gives users a gateway to selected drug information from the national library of medicine and other key government agencies. Deferoxamine dfo is an iron chelator that decreases fr production by binding with iron and decreasing the production of oh. App pharmaceuticals receives approval for deferoxamine. Tell all of your health care providers that you take deferoxamine. Deferoxamine is an ironchelating agent that binds free iron in a stable complex, preventing it from engaging in chemical reactions. Deferoxamine mesylate does not cause any demonstrable increase in the excretion of electrolytes or trace metals. Deferoxaminedesferal generic is an ironchelating agent, prescribed for acute iron poisoning and iron overload due to blood transfusion. Torrent pharmaceuticals limited is expanding its recall for.
It works by attaching to iron in the body so that it can. Deferoxamine in aneurysmal subarachnoid hemorrhage trial dash the safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Exclusivity is the sole marketing rights granted by the fda to a manufacturer upon the approval of a drug and may run simultaneously with a patent. Ibm micromedex along with its needed effects, a medicine may cause some unwanted effects. Desferal is a brand name of deferoxamine, approved by the fda in the following formulations desferal deferoxamine mesylate injectable. Apps deferoxamine mesylate is aprated, barcoded and latexfree. Approved drug list 2018, october ministry of health. Deferoxamine is an ironbinding agent that belongs to a class of drugs known as heavy metal antagonists. Exclusivity periods can run from 180 days to seven years depending upon the circumstance of the exclusivity grant. All generic drug interactions for deferoxamine inj lists will include brand and generic names. The reconstituted deferoxamine mesylate solution is an isotonic, clear and colorless to slightly yellowish solution. Although not all of these side effects may occur, if they do occur they may need medical attention. Desferal deferoxamine side effects, images, uses, dosage.
To learn more about our company, or to find information on this site, please select a topic and related category below. App will package deferoxamine mesylate in single dose vials of 500 mg, 10 ml and 2 gram, 30 ml. Read more about the prescription drug deferoxamine injection. Deferoxamine mesilate investigated as a drug and mutagen. Deferoxamine injection desferal side effects, medical. Deferoxamine mesylate supplied in vials containing 2 gm of sterile, lyophilized, powdered deferoxamine mesylate. Deferoxamine injection route side effects mayo clinic. Torrent pharmaceuticals limited is expanding its recall for losartan potassium tablets usp and losartan potassiumhydrochlorothiazide. Deferoxamine is also used to treat chronic longterm iron overload caused by repeated blood transfusions.
Deferoxamine mesylate is not indicated for the treatment of primary hemochromatosis, since phlebotomy is the method of. Desferal, deferoxamine mesylate usp, is an ironchelating agent, available in vials for intramuscular, subcutaneous, and intravenous administration. Torrent pharmaceuticals limited company information. Drugs az pill identifier supplements symptom checker diseases dictionary media. The reconstituted deferoxamine mesylate solution is an isotonic, clear and colorless to slightly yellowishcolored solution. Only select registry of toxic effects of chemical substances rtecs data is presented here.
Deferoxamine in aneurysmal subarachnoid hemorrhage trial. Deferoxamine is not to be used is patient with severe renal disease or anuria. The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice. Deferoxamine mesylate is not indicated for the treatment of primary hemochromatosis, since phlebotomy is the method of choice for removing excess iron in this disorder. Youll need to apply through each program, either online, over the phone, or with your doctors help. Mucormycosis during deferoxamine therapy is a siderophoremediated infection. Pdr drug summaries are concise pointofcare prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice pdr s drug summaries are available free of charge and serve as a great resource for us based mds, dos, nps and pas in patient practice. Information about the prescription drugs manufactured by torrent pharmaceuticals limited. Do not start, stop, or change the dose of any drug without checking with your doctor. Deferoxamine mesylate is metabolized principally by plasma enzymes. Fda finds testing issues at torrent plant fiercepharma.